GACVS supports further research to understand age-related risk because while available data suggest an increased risk in younger adults, this requires further analysis.
On the issue of sex-related risk, although more cases have been reported in females, it is important to underscore that more women have been vaccinated and that some TTS cases have also been reported in men.
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因此，需要开展进一步分析，以确定任何与性别相关的风险。
Therefore, further analysis is required to determine any sex-relatedrisk.
Clinicians should be alert to any new, severe, persistent headache or other significant symptoms, such as severe abdominal pain and shortness of breath, with an onset between 4 to 20 days after adenovirus vectoredCOVID-19 vaccination.
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作为血栓调查的一部分，各国至少应鼓励临床医生测量血小板水平，并进行适当的放射成像研究。
At a minimum, countries should encourage clinicians to measure platelet levels and conduct appropriate radiological imaging studies as part of the investigation of thrombosis.
Clinicians should also be aware that although heparin is used to treat blood clots in general, administration of heparin in TTS may be dangerous, and alternative treatments such as immunoglobulins and non-heparin anticoagulants should be considered.
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这些罕见不良事件的风险可能存在地域差异。
There may be a geographic variation in the risk of these rare adverse events.
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因此，评价所有国家的潜在血栓性血小板减少综合征病例非常重要。
It is therefore important to evaluate potential cases of TTS in allcountries.