WHO is actively following the ongoing clinical trials that are being conducted in response to COVID-19, including the more than 80 studies looking at the use of chloroquine and its derivative, hydroxychloroquine, for treatment and/or prevention.
To date, 3 large randomized controlled trials, including the WHO Solidarity trial, have failed to show that the use of hydroxychloroquine among hospitalized patients infected with COVID-19 can prevent death or disease progression.
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此外,对轻度或中度疾病患者进行的3项试验未能显示出羟氯喹在预防呼吸衰竭方面的显著益处。
Additionally, 3 trials of patients with mild or moderate disease failed to show a significant benefit in prevention of respiratory failure through the use of hydroxychloroquine.
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因此,现在有越来越多的证据表明羟氯喹不是治疗COVID-19的有效方法。
Thus, there is now growing evidence that hydroxychloroquine is not an effective treatment for COVID-19.
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这一证据将为世卫组织下一次更新治疗指导提供信息。
This evidence will inform the next update of WHOguidance on therapeutics.
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目前正在研究能否使用氯喹或羟氯喹来预防个人,特别是医务工作者等高危人群感染COVID-19。
Studies on the use of chloroquine or hydroxychloroquine to prevent individuals, particularly those at high risk such as health care workers, from contracting COVID-19 are ongoing.
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目前,没有充分证据来评估这两种药物在预防COVID-19感染或病症方面的保护效果。
Currently, there is insufficient evidence to assess the protective efficacy of either of these medicines for the prevention of COVID-19 infection or disease.