Implementation of the malaria vaccine through pilot introductions in Ghana, Kenya and Malawi has resulted in substantial reduction in deadly severe malaria and a drop in child deaths.
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作为首个安全有效的疟疾疫苗，如果该疫苗得以广泛实施，每年可以挽救数万人的生命。
The first malaria vaccine is safe and effective, and, if implemented broadly, the vaccine could save tens of thousands of lives each year.
The WHO recommendation for the malaria vaccine was informed by results from the ongoing pilot programme that has reached nearly 1.5 million children with at least one dose of vaccine since 2019.
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四年来，通过各国的常规免疫规划接种了450多万剂疫苗。
Four years on, more than 4.5 million doses of the vaccine have been administered through the countries’ routine immunization programmes.
Community demand for the vaccine is high and the vaccine is well accepted in African communities, even when additional visits to vaccination clinics are required to receive the 4-dose schedule.
Malaria vaccine introduction is led by Ministries of Health in areas of the 3 participating countries, with support from WHO and international and country-level partners, including PATH, GSK and UNICEF.
Impact and evidence Pilot introductions of the malaria vaccine in Ghana, Kenya and Malawi have resulted in substantial reduction in deadly severe malaria – a drop in child hospitalizations and reduction in child deaths The vaccine is estimated to save 1 life for every 200 children vaccinated A large phase 3 trial (2009-2014) of the RTS,S vaccine in regions of moderate to high malaria transmission showed malaria cases dropped by over half in the first year after vaccination and by 40% during 4 years of follow up.
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据估计，该疫苗每接种200名儿童可挽救1条生命。
A more recent trial (2017-2020) of the vaccine provided just prior to peak malaria season in areas with highly seasonal malaria found vaccine efficacy similar to that of Seasonal Malaria Chemoprevention (SMC), which has been shown to prevent around 75% of malaria cases.