Work is ongoing to understand whether the observed genomic changes lead to phenotypic changes such as enhanced transmissibility, virulence, immune escape, resistance to antivirals, or reduced impact of countermeasures.
Although many species of animals are known to be susceptible to the monkeypox virus in the natural setting (e.g., rope squirrels, tree squirrels, Gambian pouched rats, dormice, non-human primates), there is the potential for spillback of the virus from humans to other susceptible animal species in different settings.
To date, there is currently no documented evidence of instances of anthropozoonotic transmission available to the WHO Secretariat or its One Health partners the Food and Agriculture Organization (FAO) and the World Organisation for Animal Health (WOAH).
The WHO Secretariat also outlined the WHO response so far, and the ongoing work to develop the WHO Strategic Readiness and Response Plan for monkeypox, with its overall goal being to stop human-to-human transmission.
13685
西班牙、联合王国、美国、加拿大和尼日利亚的代表先后向委员会介绍了本国的流行状况及其目前的应对工作。
Representatives of Spain, the United Kingdom, the United States, Canada and Nigeria updated the Committee (in this order) on the epidemiological situation in their countries and their current response efforts.
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除尼日利亚外，其余四个国家报告说，99%的病例发生在男男性行为者中，主要是在有多个伴侣的人群中。
With the exception of Nigeria, the remaining four countries reported that 99% of cases were occurring in MSM, and mainly among those with multiple partners.
13687
在西班牙，过去几周病例数呈下降趋势，但由于报告延后，数据可能并不完整。
In Spain, cases have been decreasing over the past few weeks, but it is likely the data are incomplete because of delays in reporting.
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大多数病例据报发生在主要都市。
Most cases have been reported in major urban areas, with very few reports of cases among females and children who had epidemiological links to MSM.
13689
有与男男性行为存在流行病学关联的妇女和儿童罕见病例报告。
Pre-exposure prophylaxis with vaccination is being offered to health workers, contacts and people living with HIV, but vaccine supplies are low.
The United Kingdom reported on a few severe cases of monkeypox (including encephalitis), and it is also planning to modify its case definition for monkeypox, to include newly recognized conditions such as proctitis.