The multi-country outbreak of monkeypox meets all the three criteria defining a PHEIC contained in Article 1 of the Regulations ([...] an extraordinary event […] (i) constitut[ing] a public health risk to other States through the international spread of disease and (ii) which may potentially require a coordinated international response);
The moral duty to deploy all means and tools available to respond to the event, as highlighted by leaders of the LGBTI+ communities from several countries, bearing in mind that the community currently most affected outside Africa is the same initially reported to be affected in the early stages of HIV/AIDS pandemic;
13723
据观察，全球报告病例数呈上升趋势，且受影响的国家越来越多，但疫情实际规模可能仍被低估；
The observed rising trends in the number of cases reported globally, in an increasing number of countries, and, yet, likely to reflect an underestimation of the actual magnitude of the outbreak(s);
13724
报告的儿童和孕妇猴痘病例类似于艾滋病毒大流行最初阶段情况；
The cases of monkeypox reported in children and pregnant women, which are reminiscent of the initial phases of the HIV pandemic;
13725
随着猴痘病毒被引入其他易感人群，预计今后将出现大量猴痘病例；
Future waves of monkeypox cases are expected as the monkeypox virus is introduced in additional susceptible populations;
13726
尚不完全清楚当前疫情的传播方式；
The modes of transmission sustaining the current outbreak are not fully understood;
13727
目前观察到的猴痘病例临床表现与此前已知的临床情况不一样；
The changes in the clinical presentation of cases of monkeypox currently observed with respect to the clinical picture known to date;
13728
需要进一步获得关于使用药物措施和非药物措施控制疫情的有效性证据；
The need to generate further evidence related to the effectiveness of the use of both pharmaceutical and non-pharmaceutical measures in controlling the outbreak;
13729
在这次猴痘疫情中，发病率较高；
The significantmorbidity associated with the monkeypox outbreak(s);
The potential future implications on public health and health services if the disease were to establish itself in the human population across the world, particularly for an orthopoxvirus causing human disease, as global immunity has greatly declined after smallpox was eradicated;