In addition to vaccinatingcontacts and contacts of contacts, SAGE now also recommends vaccinating those who could be part of tertiary chains of transmission, such as people in villages and neighborhoods where cases have been reported within the past 21 days.
403
专家组指出,在更广泛的社区增加获得疫苗接种的机会可能有助于提高社区对疫苗和其他控制措施的接受程度。
SAGE noted that increasing access to vaccination in the broader community may help enhance community acceptance of the vaccine and other control measures.
404
专家组还建议调整目前使用的疫苗剂量。
SAGE also recommended adjusting the dose of the vaccine currently being used.
405
“专家组强调,对接触者和接触者的接触者进行环围接种仍然是首选策略。
“The SAGE emphasized that ring vaccination of contacts and contacts of contacts continues to be the preferred strategy.
However, the Working Group recognized that the current emergency and the available evidence called for a dose-adjusted approach to ensure vaccine continues to be available and offered to individuals at greatest risk of Ebola,” said Helen Rees, Co-Chair of the SAGE Ebola Vaccines Working Group.
407
高危人群(接触者和接触者的接触者)现在将获得0.5ml疫苗而不是从前的1ml。
People at highest risk (contacts and contacts of contacts) will now receive 0.5ml of vaccine instead of 1ml.
408
这与2015年在几内亚成功进行的Ebola ça suffit(法语,意为“够了,埃博拉”)环围疫苗接种试验中使用的剂量相同,且预计可带来同等程度的保护。
This dosage is equal to that used in the successful Ebola ça suffit ring vaccination trial in Guinea in 2015, and is expected to provide the same level of protection.
Those for whom a rapid evolution of the immune response is less critical (people who are considered lower-risk / those who could be potentially involved in tertiary transmission) will receive 0.2ml (1/5 of the current dose).
410
使用更多的埃博拉疫苗:正在制定部署更多疫苗的计划
Use of additional Ebola vaccines: plans for deployment of an additional vaccine underway