New guidance from the World Health Organization (WHO) sets essential standards to inform future research and development on genetically modified mosquitoes, particularly in addressing issues relating to ethics, safety, affordability and effectiveness.
9102
疟疾和其它媒介传播疾病，包括登革热和寨卡，影响全球数百万人。
Malaria and other vector-borne diseases, including dengue and Zika, affect millions globally.
9103
仅疟疾一项，每年就会导致40多万人死亡。
More than 400 000 people a year die from malaria alone.
If proven safe, effective and affordable, genetically modified vector mosquitoes could be a valuable new tool to fight these diseases and eliminate their enormous health, social and economic burden.
The guidance framework for testinggenetically modified mosquitoes, developed in partnership with TDR, the Special Programme for Research and Training in Tropical Diseases, and the GeneConvene Global Collaborative, an initiative of the Foundation for the National Institutes of Health, describes best practices to ensure that the study and evaluation of genetically modified mosquitoes as public health tools is safe, ethical and rigorous.
9106
目前限制蚊媒传播疾病的策略只是部分有效。
Current strategies for limitingtransmission of mosquito-bornediseases are only partially effective.
New, complementary approaches are needed to close the gaps in current vector control interventions, such as effective control of outdoor biting, and to provide alternatives to manage the increasing threat of insecticide resistance.
9108
研究表明，转基因蚊子可能是补充现有干预措施的一种强大且具有成本效益的工具。
Research suggests genetically modified mosquitoes could be a powerful and cost-effective tool to supplement existing interventions.
“We urgently need innovative approaches to help control mosquito-borne diseases, which have a devastating impact around the world,” said Dr John Reeder, TDR Director.
“Genetically modified mosquitoes is one such approach, but we want to be sure it’s fully and responsibly evaluated, as outlined in a recent WHO position statement.”